- Andrew Rapoza
- 7 days ago
- 12 min read
In a world of secrets, revealing a cure was revolutionary - and dangerous.
Reflecting on the brave but shaky start to our great nation on the 250th anniversary of its creation, we hold this truth to be self-evident: Life, Liberty, and the pursuit of Happiness have come at a dear price. While all three virtues were passionately pursued by the new government, they were also being sought by its citizens as the unalienable rights of personal health: everyone wanted freedom from sickness and pain, a life enshrined in health and happiness. This is the story of one early American medicine that tried to live up to those ideals.
Dirty Little Secrets
In 1790 the first U.S. patents reflected the dynamic energy of the emerging nation. Better ways of building bridges, making nails, boots, gun powder, and steam engines were all meticulously described in the new country’s earliest patent applications, along with improvements in candles, stoves, pianos, and medicine. By 1796, the United States issued its first patent for a medicine, Lee’s Bilious Pills; however, very few medicine makers applied for patents; it required revealing the medicine’s formula – the ingredients and method of manufacture – which invited duplication or public derision by competitors. Most medicine makers chose instead to operate in their self-imposed world of secrets.
Bottles and boxes of secret medicine were wrapped in gilded promises of amazing cure – but promises were hard to swallow. They were also a dubious luxury. At the turn of the 19th century, citizens of the newly united states lived on farms; well over 90% of the population survived on what they grew, raised, hunted, and made. Self-sufficiency was a requirement of their isolated existence. Although patent medicine ads were increasingly becoming regular features in newspapers and almanacs, the vast majority of rural households made their own medicines for their families and farm animals. The occasional medicine formula that also found its way into such publications was an open invitation to make their own medicine as much as a bread or pie recipe was for their next meal.
Keeping the Crew Shipshape
Philip Crandal grew up in that remote world of self-sufficiency. Samuel and Mary Crandall and their brood of 15 children lived on the expansive family farm in quiet, pastoral Tiverton, Massachusetts Bay Colony (his father’s vast tracts of field and forest stretched over to Dartmouth, Massachusetts, my home town). When Philip was fourteen, his father became “very sick and weak in body” and decided he needed to get his will quickly written. An extensive estate inventory was carefully detailed down to food vessels of earthen ware and glass, eating utensils of “Puter & wood,” and to “a box & case of bottles,” but there was absolutely no mention of medicine containers or ingredients. When Philip grew up and moved to the coast of Maine, he had a recipe for what he called Crandal’s Salve [sometimes spelled Crandel’s Salve]; it may have been a family recipe he learned to make in his youth, but it also may have been a salve he concocted as a ship master, out of necessity to take care of the wounds, aches, and pains among his crew members. He had become Captain Philip Crandal, ship master of a privateer during the American Revolution.
In 1781 he mastered a vessel named the Roebuck with guns, small arms, and a crew of sixteen men. The previous year he had been reimbursed £360 (about $110,700 in 2026 USD) by the Massachusetts’ Board of War for his services during the ill-fated Penobscot Expedition of July 1779, the worst American naval nightmare until the disaster at Pearl Harbor162 years later. Crandal’s Salve may have soothed some wounds but it wouldn’t have cured the terrible sting of defeat.
Good Deeds of the Dead
In due course, the American colonies emerged from the debacle and won the war in a few more years. Philip Crandal then lived out the rest of his life on the coast of Maine, passing away in Portland two decades later at 74 years old. In the closing years of his life, the old sea captain was approached several times by others who wanted the formula for his salve. Since it had never been sold to the public, their interest must have been piqued by stories they heard about it or experiences they themselves had with it treating various wounds, burns, and bruises. The apparent demand for the salve suggests it could have enjoyed some commercial success but Philip Crandal wanted the formula for his salve to be made freely available to his countrymen. Despite the wealth he had accumulated from inheritance and a shipping career, and the dangers he had faced while fighting for freedom from British rule in the Revolution, it’s interesting and curious that one of his final concerns was about what was to become of the small pot of greasy unguent that would, indeed, become his legacy: Crandal’s Salve.
The efficacy of Crandals Salve in cureing wounds bruises &c induced a number of gentlemen to obtain from him for a valuable compensation an exposure of the ingredients with which it was made and the maner of making it. It was however obtained upon the express condition that it Should not be made publick until the Death of Mr Crandall. This event having taken place it is thought proper as it may be of grate benefit to the public in general to publish it from the Original singed [signed] & attested to by him before a Magistrate [orthography and syntax as in original; emphasis added]
The post mortem wishes of Captain Crandal were honored to the letter: he died on 15 August 1805 and the formula for Crandal’s Salve was published less than three weeks after his demise in the Portland Gazette on 2 September. It may have been submitted to the newspaper by his only son and namesake, Philip, who had followed in his father’s wake, captaining ships in the merchant trade and getting in trouble with foreign powers during the next war. After its publication in the Portland paper, the formula for Crandal’s Salve also took sail and traveled in quick succession to The Maryland Gazette (19 September), The Luzerne Federalist (Wilkes-Barre, Pennsylvania, 11 October), The Post-Boy, and Vermont & New-Hampshire Federal Courier (Windsor, Vermont, 22 October), and The Poughkeepsie Eagle and Constitutional Republican (New York, 19 November). The readership in those regions had never heard of Crandal’s Salve, but their editors knew that free access to a new medicine formula would catch the attention of many eager eyes.

Get the Lead Out
Throughout the Northeast, the public was reading about a formula that seemed practical and useful because its ingredients were commonly known for their benefits on burns and wounds. The list of ingredients was as follows:
1 gill neatsfoot oil
1 gill linseed oil
¼ lb white lead
¼ lb red lead
½ oz gum of myrrh
½ oz camphor
3 oz rosin
1½ oz beeswax
a large tablespoonful of West Indian
rum "for what I call half a mess" [measure]
The problem with these ingredients – the very, very big problem – was the use of white and red lead. In any color, lead is an extremely toxic heavy metal; even the smallest exposure to the body is hazardous, tragic, and often deadly, whether it was swallowed, inhaled, or, as with Crandal’s Salve, absorbed through the skin. Like a barrage of bullets, lead targets the whole body; depending on the amount of exposure, serious damage to the brain, blood, heart, skin, kidneys, nervous system, and reproductive organs can develop slowly over months and years or quickly, within days or hours. Pregnant women and children are especially vulnerable. In total, there was a half-pound of lead in Crandal’s Salve – 36% of the recipe’s total volume when even a thimbleful would have been plenty dangerous. The salve was providing extremely temporary relief for a lifetime of misery, whatever lifetime was left.
In my lifetime, lead has been removed from paint, toys, water pipes, dinnerware, cookware, cosmetics, and gasoline, but Crandal’s Salve was being made in 1805, not 2025. No one back then had a clue that it was harmful and dangerous. Then in 1825, fully twenty years after the formula for Crandal’s Salve had been introduced in the Portland Gazette, it was resurrected by none other than the Boston Medical Intelligencer, a publication in alignment with the educated medical establishment in Massachusetts. Three days later, the New England Farmer was quick to copy it onto their pages from the Intelligencer, effectively reintroducing it to a whole new generation of the general public.
It Must Be Okay – Everybody’s Doing It
Shortly after the 1825 reprints of the Crandal’s Salve formula, the passion for recipes and formulas to help with home economy and self-sufficiency grew into book form – collections of “how-to” recipes and formulas primarily designed for use in the home. They almost always contained a combination of food recipes and medicine formulas (which were often designed for man and beast, enabling farmers to take care of their draught animals and livestock), and the more robust volumes included formulas helpful to tradesmen like barbers, blacksmiths, painters, and merchants. Some of these massive collections were extremely popular, but with all the improvements the century brought, they still didn’t get the lead out of their medicinal recipes. Leading the way were Lydia Maria Child’s American Frugal Housewife, in which she gave her formula of lead in rosewater for the relief of a nursing mother’s sore nipples, and Dr. Chase’s Recipes; or, Information for Everybody, which instructed how to make a salve for burns from beeswax, opium, and lead; an eye water made of tobacco, lead, opium, and rain water; and laying a sheet of lead on the chest “for days or weeks” to fight cancer. First printed in 1828 and 1856, respectively, these two books were huge best-sellers in that genre; Child’s book went through over 30 editions within a decade, and Chase’s encyclopedic work claimed that by 1867 it was in its 49th edition with over 358,000 copies printed; by 1915 over four million copies had been sold.
Dr. Baxter’s Legacy
The single piece of ephemeral evidence of Crandal’s Salve in my collection is a tattered copy of the original formula on old, watermarked bond that had once been in the possession of Dr. Elihu Baxter (1781-1863). He was born in Vermont and attended two courses of lectures at Dartmouth College in Hannover, New Hampshire, graduating in 1802. He set up his medical practice in the village of Lemington, Vermont, along the Connecticut River in the state’s remote northern reaches. There he got married in frigid February 1806 during a snowstorm.
Grief brought him to coastal Maine and the formula for Crandal’s Salve. Six weeks after their white-out wedding, Dr. Baxter’s 18-year-old bride, Clarissa, attempted to cross the iced-over Connecticut River on horseback, but the ice broke and Clarissa (and most likely her horse as well) disappeared into the icy depths; she drowned, her body never to be found. A boy first broke the news to Dr. Baxter, who reacted with anger, assuming it was a bad joke since it was April 1st, known even then as April Fool’s Day. But as other messengers followed quickly with the same tragic news, it was Dr. Baxter’s heart that broke. An account of the tragedy stated, “The young physician was overcome with grief and soon wearied of the place where he had lost his young wife,” so he moved to Maine, eventually ending up in Gorham, outside of Portland.
He became wealthy and well-established in the community, and the patriarch of a prominent Maine family: one of his sons became a mayor in Portland and one of his grandsons would become a governor of Maine. Dr. Baxter distinguished himself in his medical career, willing to take an unpopular position on controversial medical issues; he was one of the first physicians in Gorham to advocate vaccination as a preventative for smallpox. An admiring fellow doctor called him “a physician rather ahead of his time,” but he didn't have to be an eccentric medical maverick to advocate Crandal's Salve – in 1825 it was a typical salve composed of standard ingredients for wounds and bruises. So it comes as no surprise that Dr. Baxter was apparently one of the “gentlemen” that requested and paid Captain Crandal's son for the salve formula. I have found no evidence of his daybooks or other records documenting his practice, so he may or may not have incorporated the salve into his personal prescribing formulary; however, he apparently thought highly enough of Crandal’s salve formula to eventually pass it on or sell it (either means of transmission by a doctor would have been considered unethical if he considered it ineffective or dangerous) to another gentleman, Hugh D(avis) McLellan, a young merchant in Gorham.
McLellan’s Boondoggle
A somewhat enigmatic note is written on the back of the copy of the Crandal’s Salve formula that I own; it reads:
A Receipt for
Crandels Salve .. from
Dr Elihu Baxter .. To
Hugh D McLellan
From the 2 after the origin
al [original]

“From the 2 after the original” is a perplexing notation; perhaps this copy that Dr. Baxter was handing off to McLellan was a copy of a prior revision of the original, but it bears no evidence of a change in ingredients or directions from the first version printed in the newspaper back in 1805. The curious phrase seems more likely to be a count in the formula’s ownership lineage, going from Philip Crandal, the son of the salve’s creator, to Dr. Baxter (the “2 after the original”) before it came into the custody of McLellan. Assuming that Hugh D. McLellan of Gorham, Maine, wouldn’t have been professionally interested in the salve until he was at the age of his majority (21) in 1826 while getting into business as a merchant in Gorham, and given that Dr. Baxter left Gorham in 1831, it seems
most likely that Dr. Baxter gave McLellan the formula for the salve between 1826-1831. McLellan eventually wrote a history of Gorham containing a few biographical lines about Dr. Baxter, whom he clearly knew. These included the observation that Dr. Baxter had “a lasting reputation as a good citizen and a faithful and successful physician.” McLellan trusted and admired the physician who was giving (or selling) him this salve formula. The next question is, did merchant McLellan take ownership of the formula in order to produce tins of the salve for sale in his store? Was he going to dishonor its creator’s last wish by selling it as a nostrum instead of giving it away freely to all?
As best as I can tell, the answer was no. Advertisements for McLellan’s store in 1836 and 1838 listed scores of items for sale, but they didn’t mention any kind of salve. One of the 1838 ads was especially comprehensive, listing dozens of items from shaving soap, raisins, pepper sauce, thread, forks, and pen knives, to cigars, sugar, and “Preston’s Prepared Cocoa, the best preparation of Cocoa ever made, for the sick, or those in health” – but no salve. McLellan’s History of Gorham, Maine, also made no mention of the salve. If McLellan had purchased the salve recipe for profit, he either gave up on the idea or the result.
Kids, Don’t Try This at Home!
The centuries-old formula eventually found its way into the hands of my friend and fellow historian, Jim Schmidt, and he has now entrusted it to me, it’s current steward. And so I will close this blog post with the formula that Captain Philip Crandal wanted to share with the world; it’s my tribute to him, perpetuating it as he had hoped, making it available in all its toxic, dangerous, deadly glory. Although it’s a cure for nothing (other than perhaps staying healthy and alive), it can serve as a reminder of the blessings we have in modern medicine. Our science is still far from perfect, but at least we’re getting the lead out.
A Receipt for Making Crandals Salve
The Maner of Making as Follows Viz
1st Take the Neats foot Oil and put it into a mug that has not ben used or greased (it must be an earthan mug and nothin els) & boil it, keep stirring it untill it has done sparkling then put in the White Lead & keep stiring it untill it begins to rise Braking the lumps and taking out the gravel if thare be any then put in the red Lead and do the same being carful to Put in no grit; Boil this mixture untill the color turns, not boiling it too much and be careful not to let it boil over then let it cool a little and then add the Gum of Myrrh then the Camphor then the Roosin then the Bees wax stiring it after one ingredient be put in so that thay may be well mixed before you put in another after all these are added. then put in the Rum drop after Drop when it coolls a little so as not to let it foam and run over keep it stiring until it has got Cool and then it is made. Philip Crandel [orthography and syntax as in original]
















